U-2-11 AF

論文抄録

STUDY OBJECTIVE: To determine the comparative efficacy of i.v. metoclopramide and prochlorperazine for the initial emergency department treatment of migraine headache. DESIGN: Prospective, randomized, double-blind, placebo-controlled trial. SETTING: Military community hospital ED with an annual census of 75,000. PARTICIPANTS: Seventy consenting adults from a convenience sample of patients presenting with migraine headache similar to that experienced in at least one prior episode.

occular myesthenia無力症の痛みの症状

Exclusion criteria were pregnancy, fever, signs of meningismus, altered sensorium, drug or alcohol use, oxygen saturation less than 90%, recent trauma or seizure, "worst headache," abnormal blood pressure, recent (within 48 hours) use of metoclopramide or prochlorperazine, and allergy to metoclopramide or prochlorperazine. INTERVENTIONS: In a random manner, each subject received a 2-mL i.v. injection of identical-appearing fluid containing metoclopramide (10 mg), prochlorperazine (10 mg), or saline solution (placebo). No other analgesics or medications were administered during the initial study period; rescue agents were administered by the choice of the treating physician after all data were collected. MEASUREMENTS: Patients scored their nausea, pain, and sedation before receiving the 2-mL injections and at 30 minutes after injection.

chonic痛み

Ten-centimeter nonhatched visual analog scales were used for these measurements, with distance from the left end (zero) calculated for each use. Clinically important successful treatment was defined a priori as achievement of the following criteria: patient satisfaction and either a decrease of 50% or more in the 30-minute pain score (compared with the initial score) or an absolute pain score of 2.5 cm or less. Failure to achieve these criteria constituted treatment failure. Differences between groups were analyzed with the Kruskal-Wallis ANOVA and chi 2 tests. Data are reported as frequency percentages and median values, with a two-tailed P value of .05 or less considered significant. RESULTS: Nausea, pain, and sedation scores were similar in all three groups before therapy. Thirty minutes after treatment, pain scores differed among those treated with prochlorperazine (1.1 cm), with metoclopramide (3.

慢性うつ病疲労症候群

9 cm), and with placebo (6.1 cm, P = .003). Clinical success occurred more commonly after treatment with prochlorperazine (82%) than after metoclopramide (46%) or placebo (29%, P = .03). However, metoclopramide and placebo scores did not differ (P = .14). Nausea tended to be improved after prochlorperazine, compared with metoclopramide or placebo, at 30 minutes (P = .64). Four patients (6%) returned to the ED for relapse of migraine headache within 24 hours (three in the placebo group and one in the metoclopramide group). CONCLUSION: i.v. prochlorperazine relieves the headache and tends to improve nausea better than metoclopramide in ED patients with acute migraine headache
 

These are our most popular posts:

薬 - 文辞郎

歯痛の薬ありますか？」「アスピリンがあります」 Do you have anything for a toothache? We have aspirin. 鎮痛剤［痛み止め］を下さい。 I need a pain killer. 吐き気止めの薬はありませんか？ Do you have some medicine for nausea? 船酔い です。 read more

アメリカ在住者のお薦め商品～医薬品

背中の痛み（肩こり・腰痛）、頭痛、歯痛、風邪の諸症状、月経痛、関節痛 -Tylenol Arthritis Pain（効き目の長い鎮痛剤）18歳以上 ..... （nausea＝胃のむかつき） 食べすぎ 、飲みすぎにともなう胃のもたれ、不快感、 膨満感、胸やけ リキッドタイプもある。 Nausea ... read more

Ⅱ-2-11 AF

Patients rated their pain and nausea at time 0, 30 minutes, and 60 minutes using visual-analog scales. RESULTS: The differences ... 制吐剤メトクロプラミド単独と 鎮痛剤 イブプロフェンとの合剤の片頭痛治療効果を評価. 研究デザイン. a randomized ... read more

その圏内にいる人に頭痛を引き起こす「Sonic Nausea」

頭痛外来･頭痛治療の専門外来 その圏内にいる人に頭痛を引き起こす「Sonic Nausea 」情報です。 ... たいていの人は鎮痛剤を飲んで、頭痛を紛らわしているかと思いますが、 頭痛にもいろいろな種類があり片頭痛、緊張性頭痛、群発性頭痛などという種類 ... read more